PANcreatic CAncer Initial Detection via liquid biopsy

Publication alert! 📣
Pancreatic incidentaloma: incidental findings from history towards the era of liquid biopsy.
The authors, Matthias Löhr (KI), Miroslav Vujasinovic, Nikolaos Kartalis, and Philipp Osten discuss:
✨ most common diagnostic methods
✨ impact of medical imaging
✨ ethical perspectives of screening

Open access 🔓 https://egastroenterology.bmj.com/content/2/3/e100082

Kim-Lea Reese, Prof. Dr. Klaus Pantel and Dr. Dr. Daniel Smit, all members of partner UKE working on Work Package 2 (WP2), have published a review article! This paper, published in Journal of Experimental &
Clinical Cancer Research, provides overview of different liquid biopsy biomarkers for the early diagnosis of pancreatic ductal adenocarcinoma (PDAC) and discuss the validity of multimarker panels.

Single biomarkers discussed include cellular biomarkers, circulating nucleic acids, proteins, and extracellular vesicles. The article is enriched with an extensive section about the current findings on multimarker panels.

Read the full article here 🔓: https://jeccr.biomedcentral.com/articles/10.1186/s13046-024-03166-w

PANCAID’s second General Assembly Meeting took place at our partner CNIO from 17 to 19 January 2024. During the first half day, the consortium first witnessed a masterclass given by esteemed Francisco X. Real, MD, PhD, Senior Group Leader at CNIO and current chair of the CNIO Scientific Committee on “the topic of “Molecular pathophysiology of pancreatic ductal adenocarcinoma (PDAC)”. After this stellar lecture, PANCAID’s Early Career Scientists (ECS) each presented themselves as well as their work.

On the second day, after a warm welcome by the project coordinator Klaus Pantel, co-coordinator Matthias Löhr as well as CNIO members Núria Malats and Héctor Peinado, the meeting commenced with updates on the diverse work packages, plenum discussions and presentation of our Scientific and Ethical Advisory Board (SEAB) members.

The last day kicked off with a keynote lecture by Ellen Heitzer from our partner MUG on “Liquid biopsy in PDAC – Current status & implications for PANCAID”, followed by updates on the remaining work packages. The meeting was rounded off with valuable feedback from the SEABs and a final discussion led by the coordinators.