The Chancellor Masters and Scholars of the University of Cambridge (UCAM)

Team Leaders

Institute Presentation

The University of Cambridge is one of the world’s oldest and most successful universities. We are a renowned centre for research, education and scholarship that makes a significant contribution to society. The University is consistently ranked amongst the top universities in the world, and our affiliates have won more Nobel Prizes than any other University.

The Cancer Research UK Cambridge Institute was established in 2007, and is a part of the University of Cambridge. The Institute is located on the Cambridge Biomedical Campus and is Europe’s largest centre of health science and medical research providing unique access to both the clinic and industry. The institute’s goal is to combine world-leading basic cancer biology with key technologies to bear on practical questions of cancer diagnosis, treatment and prevention. The Institute has particular strengths in genomics, computational biology, and imaging, and currently devotes significant research effort to understand the fundamental biology of cancer and to translate these findings into the clinic to benefit patients.

The Rosenfeld laboratory is based in the CRUK Cambridge Institute has particular expertise in next generation sequencing approaches to ultra-sensitive circulating tumour DNA detection, and in the detection strategies in minute amounts of blood such as dried blood spots. Our role in PANCAID is to develop and apply tumour-informed approaches for high sensitivity cancer detection in the minimal residual disease (MRD) setting, developing strategies for multi-omic integration of cfDNA methods, and advancing the use of dried blood spot sampling for home monitoring of PDAC.